| Pimozide |
Influence on proteins |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on proteins |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
STAT5 |
|
| Pimozide |
Influence on proteins |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on proteins |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
1.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
3.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
7.50 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
10.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on proteins in presece of PKC412 |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on proteins in presece of PKC412 |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
STAT5 |
|
| Pimozide |
Influence on cell viability in presence of PKC412 |
ATP-dependent luminescence assay |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell apoptosis in presence of PKC412 |
Flow cytometry- Annexin |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on protein activity in presence of sunitinib |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on protein activity in presence of sunitinib |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
STAT5 |
|
| Pimozide |
Influence on cell viability in presence of sunitinib |
ATP-dependent luminescence assay |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell apoptosis in presence of sunitinib |
Flow cytometry- Annexin |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on tumor growth |
Body weight |
25.00 mg/kg |
Ba/f3 FLT3 ITD luc+ |
Mus musculus |
NCr nude mice |
|
|
| Pimozide |
Influence on tumor growth |
Average survival |
25.00 mg/kg |
Ba/f3 FLT3 ITD luc+ |
Mus musculus |
NCr nude mice |
|
|
| Pimozide |
Influence on tumor growth |
Relative bioluminescence |
25.00 mg/kg |
Ba/f3 FLT3 ITD luc+ |
Mus musculus |
NCr nude mice |
|
|
